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Serenin Max combines natural ingredients that work together to promote normal behavioral patterns and a healthy nervous system, particularly in times of stress.

60 Capsules Per Bottle
Product Code: NN121
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Price for US Customers Only
Serenin Max provides natural ingredients to promote normal, calm behavioral patterns, particularly during times of stress, and to maintain a healthy nervous system and brain function supporting healthy cognition. These ingredients work together to achieve this calming effect and include:
  • St. John’s Wort extract, with active constituents hyperforin and hypericin, promotes healthy mentation and behavioral patterns by modulating serotonin, dopamine, and norepinephrine; reducing serotonin reuptake in the brain; and inhibiting GABA ligand binding.1
  • Eleuthero powder, an adaptogen, aids in the body’s ability to cope with environmental stress and anxiety by modulating the nitric oxide and cortisol production via the hypothalamic-pituitary axis.2
  • Passion flower extract, containing flavonoids and alkaloids, promote relaxation by inhibiting GABA uptake by nerve cell synapses.3
  • DL-phenylalanine is a form of an essential amino acid that promotes normal mood and behavior via two mechanisms. First, phenylalanine is a precursor for norepinephrine production and helps to maintain healthy amounts of the neurotransmitter. Second, phenylalanine is metabolized to the neuromodulator 2-phenylethylamine. An increase in the production of this metabolite helps to maintain normal mood and attention either by greater available concentration or by improvement of brain neuron receptor sensitivity.4
    NOTE: If pregnant or lactating, please discuss with your doctor before use.
  • 5-HTP (Griffonia simplicifolia seed), a metabolite produced from essential amino acid L-tryptophan and a direct precursor for serotonin production in the CNS that promotes serotonin production and thereby healthy behavioral responses in times of stress.5


1 Butterweck V, Wall A, Lieflander-Wulf U, Winterhoff H, and Nahrstedt A. Effects of the total extract and fractions of Hypericum perforatum in animal assays for antidepressant activity. Pharmacopsychiatry. 1997; 30(Suppl 2): 117-124.

2 Wilson L. Review of adaptogenic mechanisms: Eleuthrococcus senticosus, Panax ginseng, Rhodiola rosea, Schisandra chinensis, and Withania somnifera. Australian Journal of Medical Herbalism. 2007; 19(3): 126-131.

3 Appel K, Rose T, Fiebich B, Kammler T, Hoffman C, and Weiss G. Modulation of the γ-aminobutyric acid (GABA) system by Passifora incarnata L. Phytother Res. 2011; 25(6): 838-843.

4 Kravitz HM, Sabelli HC, and Fawcett J. Dietary supplements of phenylalanine and other amino acid precursors of brain neuroamines in the treatment of depressive disorders. J Am Osteopath Assoc. 1984; 84(1 Suppl): 119-123.

5 Birdsall TC. 5-Hydroxytryptophan: A clinically effective serotonin precursor. Altern Med Rev. 1998; 3: 271-280.

Weight (lbs.) Daily Use
Any Take two (2) capsules as a dietary supplement, or as directed by a qualified health care professional.

Uso Sugerido: Tomar dos (2) capsulas diarias como suplemento nutricional o segun indicacion medical.

Serving Size: 1 Capsules
Capsules Per Bottle: 60
Ingredient Amount Per Serving
Vitamin B-6 (as pyridoxine HCl) 25 mg
Folate (as folic acid) 400 mcg
Vitamin B-12 (as cyanocobalamin) 200 mcg
Magnesium (as magnesium oxide) 100 mg
Selenium (as selenium amino acid chelate) 70 mcg
5-HTP (L-5-hydroxy-tryptophan (Griffonia simplicifolia) (seed) 25 mg
DL- Phenylananine 40 mg
Eleuthero powder (Eleutherococcus senticosus)(rhizome) 70 mg
Inositol 100 mg
L-Tyrosine 10 mg
St. John's Wort extract (Hypericum perforatum)(flower heads)(std. for 0.3% Hypericin (1.8 mg)) 600 mg
Passion Flower extract (Passiflora incarnata) (aerial parts)(std. for >3.5% flavonoids as Isovetexin (1.75 mg)) 50 mg
Other Ingredients: Rice flour, Gelatin, Magnesium stearate, Amorphous silica gel, Maltodextrin.

Contains: corn, rice, animal products (beef, pork).
Extra Information:
This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten or corn. Contains NO sugar, artificial sweeteners, flavors, colors, or preservatives.